منابع مشابه
Interplay of PKA and Rac
Cellular membrane receptors sense environmental changes and relay the reshaped signal through spatially and temporally organized protein-protein interactions (PPI). Many of such PPI are transient and occur in a certain cell-dependent context. Molecular switches such as kinases and GTPases are engaged in versatile PPI. Recently, we have identified dynamic interaction and reciprocal regulation of...
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In the crystal structure of the racemic title compound, C(22)H(29)N(2)O(3) (+)·Cl(-), both NH groups form N-H⋯Cl hydrogen bonds with the chloride counter-ion, forming translational chains along the a axis.
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THE TITLE COMPOUND (SYSTEMATIC NAME rac-3,3,3-trifluoro-2-hy-droxy-propanoic acid), C3H3F3O3, is a fluorinated derivative of lactic acid. The O=C-C-O(H) torsion angle is 13.26 (15)°. In the crystal, O-H⋯O hydrogen bonds and C-H⋯O contacts connect the mol-ecules into sheets perpendicular to the c axis.
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It takes time, money and staff, but hospitals can get their arms around the RAC process.
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The racemic title compound, C(3)H(5)Br(2)NO, was crystallized from methanol. In the crystal, adjacent mol-ecules are linked through N-H⋯O hydrogen bonds, forming chains along the c-axis direction. These chains are linked through N-H⋯O hydrogen bonds, forming an undulating two-dimensional network lying parallel to the bc plane. There are also short Br⋯Br contacts present [3.514 (3) Å].
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2018
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2018.09.007